3did: interacting protein domains of known three-dimensional structure
Author(s) -
Amelie Stein
Publication year - 2004
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gki037
Subject(s) - biology , domain (mathematical analysis) , gene ontology , computational biology , ontology , protein domain , protein structure database , protein–protein interaction , exploit , protein structure , gene , genetics , computer science , mathematical analysis , philosophy , gene expression , mathematics , computer security , epistemology , sequence database , biochemistry
The database of 3D Interacting Domains (3did) is a collection of domain-domain interactions in proteins for which high-resolution three-dimensional structures are known. 3did exploits structural information to provide critical molecular details necessary for understanding how interactions occur. It also offers an overview of how similar in structure are interactions between different members of the same protein family. The database also contains Gene Ontology-based functional annotations and interactions between yeast proteins from large-scale interaction discovery studies. A web-based tool to query 3did is available at http://3did.embl.de.
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