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ACMES: fast multiple-genome searches for short repeat sequences with concurrent cross-species information retrieval
Author(s) -
Joseph Reneker,
ChiRen Shyu,
P.Y. Zeng,
Joe C. Polacco,
Walter Gassmann
Publication year - 2004
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkh455
Subject(s) - biology , hash function , genome , gene ontology , information retrieval , web server , computational biology , function (biology) , gene , genetics , computer science , the internet , world wide web , gene expression , computer security
We have developed a web server for the life sciences community to use to search for short repeats of DNA sequence of length between 3 and 10,000 bases within multiple species. This search employs a unique and fast hash function approach. Our system also applies information retrieval algorithms to discover knowledge of cross-species conservation of repeat sequences. Furthermore, we have incorporated a part of the Gene Ontology database into our information retrieval algorithms to broaden the coverage of the search. Our web server and tutorial can be found at http://acmes.rnet.missouri.edu.

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