BLAST: at the core of a powerful and diverse set of sequence analysis tools | Zendy

Scott McGinnis | Zendy; Thomas Madden | Zendy

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BLAST: at the core of a powerful and diverse set of sequence analysis tools

Author(s) -

Scott McGinnis,

Thomas Madden

Publication year - 2004

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkh435

Subject(s) - selection (genetic algorithm) , set (abstract data type) , biology , sequence (biology) , variety (cybernetics) , resource (disambiguation) , sequence alignment , domain (mathematical analysis) , core (optical fiber) , information retrieval , computer science , artificial intelligence , genetics , programming language , computer network , peptide sequence , mathematical analysis , telecommunications , mathematics , gene

Basic Local Alignment Search Tool (BLAST) is one of the most heavily used sequence analysis tools available in the public domain. There is now a wide choice of BLAST algorithms that can be used to search many different sequence databases via the BLAST web pages (http://www.ncbi.nlm.nih.gov/BLAST/). All the algorithm-database combinations can be executed with default parameters or with customized settings, and the results can be viewed in a variety of ways. A new online resource, the BLAST Program Selection Guide, has been created to assist in the definition of search strategies. This article discusses optimal search strategies and highlights some BLAST features that can make your searches more powerful.

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