MotifViz: an analysis and visualization tool for motif discovery | Zendy

Yutao Fu | Zendy; Martin C. Frith | Zendy; Peter M. Haverty | Zendy; Zhiping Weng | Zendy

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MotifViz: an analysis and visualization tool for motif discovery

Author(s) -

Yutao Fu,

Martin C. Frith,

Peter M. Haverty,

Zhiping Weng

Publication year - 2004

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkh426

Subject(s) - biology , motif (music) , visualization , computational biology , sequence motif , web server , transcription factor , structural motif , transcription (linguistics) , genetics , gene , bioinformatics , the internet , world wide web , computer science , data mining , linguistics , physics , philosophy , acoustics , biochemistry

Detecting overrepresented known transcription factor binding motifs in a set of promoter sequences of co-regulated genes has become an important approach to deciphering transcriptional regulatory mechanisms. In this paper, we present an interactive web server, MotifViz, for three motif discovery programs, Clover, Rover and Motifish, covering most available flavors of algorithms for achieving this goal. For comparison, we have also implemented the simple motif-matching program Possum. MotifViz provides uniform and intuitive input and output formats for all four programs. It can be accessed at http://biowulf.bu.edu/MotifViz.

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