GOblet: a platform for Gene Ontology annotation of anonymous sequence data | Zendy

Detlef Groth | Zendy; Hans Lehrach | Zendy; Steffen Hennig | Zendy

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GOblet: a platform for Gene Ontology annotation of anonymous sequence data

Author(s) -

Detlef Groth,

Hans Lehrach,

Steffen Hennig

Publication year - 2004

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkh406

Subject(s) - annotation , biology , java applet , java , gene ontology , sequence (biology) , web server , web application , sequence database , ontology , biological data , computer science , gene , database , computational biology , world wide web , bioinformatics , programming language , the internet , genetics , gene expression , philosophy , epistemology

GOblet is a comprehensive web server application providing the annotation of anonymous sequence data with Gene Ontology (GO) terms. It uses a variety of different protein databases (human, murines, invertebrates, plants, sp-trembl) and their respective GO mappings. The user selects the appropriate database and alignment threshold and thereafter submits single or multiple nucleotide or protein sequences. Results are shown in different ways, e.g. as survey statistics for the main GO categories for all sequences or as detailed results for each single sequence that has been submitted. In its newest version, GOblet allows the batch submission of sequences and provides an improved display of results with the aid of Java applets. All output data, together with the Java applet, are packed to a downloadable archive for local installation and analysis. GOblet can be accessed freely at http://goblet.molgen.mpg.de.

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