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SCit: web tools for protein side chain conformation analysis
Author(s) -
Romain Gautier,
AnneClaude Camproux,
Pierre Tufféry
Publication year - 2004
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkh388
Subject(s) - side chain , biology , protein structure , web server , computational biology , client side , stereochemistry , crystallography , biochemistry , computer science , world wide web , chemistry , the internet , organic chemistry , polymer
SCit is a web server providing services for protein side chain conformation analysis and side chain positioning. Specific services use the dependence of the side chain conformations on the local backbone conformation, which is described using a structural alphabet that describes the conformation of fragments of four-residue length in a limited library of structural prototypes. Based on this concept, SCit uses sets of rotameric conformations dependent on the local backbone conformation of each protein for side chain positioning and the identification of side chains with unlikely conformations. The SCit web server is accessible at http://bioserv.rpbs.jussieu.fr/SCit.

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