IntAct: an open source molecular interaction database | Zendy

Henning Hermjakob | Zendy; Luisa MontecchiPalazzi | Zendy; Christopher P. Lewington | Zendy; Sugath Mudali | Zendy; Samuel Kerrien | Zendy; Sandra Orchard | Zendy; Martin Vingron | Zendy; Bernd Roechert | Zendy; Peter Roepstorff | Zendy; Alfonso Valencia | Zendy; Hanah Margalit | Zendy; J. T. Armstrong | Zendy; Amos Bairoch | Zendy; Gianni Cesareni | Zendy; David James Sherman | Zendy; Rolf Apweiler | Zendy

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IntAct: an open source molecular interaction database

Author(s) -

Henning Hermjakob,

Luisa MontecchiPalazzi,

Christopher P. Lewington,

Sugath Mudali,

Samuel Kerrien,

Sandra Orchard,

Martin Vingron,

Bernd Roechert,

Peter Roepstorff,

Alfonso Valencia,

Hanah Margalit,

J. T. Armstrong,

Amos Bairoch,

Gianni Cesareni,

David James Sherman,

Rolf Apweiler

Publication year - 2003

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkh052

Subject(s) - context (archaeology) , consistency (knowledge bases) , biology , xml , interface (matter) , computer science , database , graphical user interface , software , world wide web , information retrieval , computational biology , programming language , operating system , paleontology , bubble , artificial intelligence , maximum bubble pressure method

IntAct provides an open source database and toolkit for the storage, presentation and analysis of protein interactions. The web interface provides both textual and graphical representations of protein interactions, and allows exploring interaction networks in the context of the GO annotations of the interacting proteins. A web service allows direct computational access to retrieve interaction networks in XML format. IntAct currently contains approximately 2200 binary and complex interactions imported from the literature and curated in collaboration with the Swiss-Prot team, making intensive use of controlled vocabularies to ensure data consistency. All IntAct software, data and controlled vocabularies are available at http://www.ebi.ac.uk/intact.

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