GenePaint.org: an atlas of gene expression patterns in the mouse embryo | Zendy

Axel Visel | Zendy

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GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Author(s) -

Axel Visel

Publication year - 2003

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkh029

Subject(s) - biology , panning (audio) , zoom , gene expression , identifier , gene , embryo , in situ hybridization , computational biology , atlas (anatomy) , embryonic stem cell , genetics , anatomy , computer science , paleontology , programming language , lens (geology)

High-throughput instruments were recently developed to determine gene expression patterns on tissue sections by RNA in situ hybridization. The resulting images of gene expression patterns, chiefly of E14.5 mouse embryos, are accessible to the public at http://www.genepaint.org. This relational database is searchable for gene identifiers and RNA probe sequences. Moreover, patterns and intensity of expression in approximately 100 different embryonic tissues are annotated and can be searched using a standardized catalog of anatomical structures. A virtual microscope tool, the Zoom Image Server, was implemented in GenePaint.org and permits interactive zooming and panning across approximately 15,000 high-resolution images.

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