APD: the Antimicrobial Peptide Database
Author(s) -
Zhe Wang
Publication year - 2003
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkh025
Subject(s) - peptide , biology , antifungal , database , antimicrobial peptides , antimicrobial , antibacterial peptide , computational biology , peptide sequence , web browser , bioinformatics , computer science , antibacterial activity , genetics , biochemistry , world wide web , bacteria , microbiology and biotechnology , the internet , gene
An antimicrobial peptide database (APD) has been established based on an extensive literature search. It contains detailed information for 525 peptides (498 antibacterial, 155 antifungal, 28 antiviral and 18 antitumor). APD provides interactive interfaces for peptide query, prediction and design. It also provides statistical data for a select group of or all the peptides in the database. Peptide information can be searched using keywords such as peptide name, ID, length, net charge, hydrophobic percentage, key residue, unique sequence motif, structure and activity. APD is a useful tool for studying the structure-function relationship of antimicrobial peptides. The database can be accessed via a web-based browser at the URL: http://aps.unmc.edu/AP/main.html.
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