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LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system
Author(s) -
Danika L. Bannasch,
Alexander Mehrle,
Karl Heinz Glatting,
Rainer Pepperkok,
Poustka Annemarie,
Stefan Wiemann
Publication year - 2003
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkh022
Subject(s) - biology , orfs , genomics , functional genomics , computational biology , proteomics , complementary dna , sample (material) , interface (matter) , ensembl , genome , bioinformatics , genetics , gene , open reading frame , peptide sequence , pulmonary surfactant , biochemistry , chemistry , gibbs isotherm , chromatography
We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on the encoded proteins produced in functional genomics and proteomics approaches. The database also serves as a sample-tracking system to manage the process from cDNA to experimental read-out and data interpretation. A web interface enables the scientific community to explore and visualize features of the annotated cDNAs and ORFs combined with experimental results, and thus helps to unravel new features of proteins with as yet unknown functions.

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