Tcoffee@igs: a web server for computing, evaluating and combining multiple sequence alignments | Zendy

Olivier Poirot | Zendy

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Tcoffee@igs: a web server for computing, evaluating and combining multiple sequence alignments

Author(s) -

Olivier Poirot

Publication year - 2003

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkg522

Subject(s) - web server , biology , sequence (biology) , multiple sequence alignment , documentation , tree (set theory) , sequence alignment , phylogenetic tree , set (abstract data type) , computer science , computational biology , bioinformatics , operating system , the internet , genetics , peptide sequence , programming language , gene , mathematical analysis , mathematics

This paper presents Tcoffee@igs, a new server provided to the community by Hewlet Packard computers and the Centre National de la Recherche Scientifique. This server is a web-based tool dedicated to the computation, the evaluation and the combination of multiple sequence alignments. It uses the latest version of the T-Coffee package. Given a set of unaligned sequences, the server returns an evaluated multiple sequence alignment and the associated phylogenetic tree. This server also makes it possible to evaluate the local reliability of an existing alignment and to combine several alternative multiple alignments into a single new one. Tcoffee@igs can be used for aligning protein, RNA or DNA sequences. Datasets of up to 100 sequences (2000 residues long) can be processed. The server and its documentation are available from: http://igs-server.cnrs-mrs.fr/Tcoffee/.

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