Multiple sequence alignment with the Clustal series of programs | Zendy

Chenna Ramu | Zendy

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Multiple sequence alignment with the Clustal series of programs

Author(s) -

Chenna Ramu

Publication year - 2003

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/gkg500

Subject(s) - biology , multiple sequence alignment , software portability , phylogenetic tree , sequence alignment , web server , indel , robustness (evolution) , bioinformatics , set (abstract data type) , computational biology , computer science , the internet , genetics , world wide web , peptide sequence , programming language , gene , single nucleotide polymorphism , genotype

The Clustal series of programs are widely used in molecular biology for the multiple alignment of both nucleic acid and protein sequences and for preparing phylogenetic trees. The popularity of the programs depends on a number of factors, including not only the accuracy of the results, but also the robustness, portability and user-friendliness of the programs. New features include NEXUS and FASTA format output, printing range numbers and faster tree calculation. Although, Clustal was originally developed to run on a local computer, numerous Web servers have been set up, notably at the EBI (European Bioinformatics Institute) (http://www.ebi.ac.uk/clustalw/).

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