Open AccessA PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration
Author(s) -
You Wu,
Wang Luo,
Zhi Weng,
Yongcan Guo,
Hongyan Yu,
Rong Zhao,
Li Zhang,
Jie Zhao,
Dan Bai,
Xi Zhou,
Lin Song,
Kena Chen,
Junjie Li,
Yujun Yang,
Guoming Xie
Publication year - 2022
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkac886
Subject(s) - crispr , biology , palindrome , computational biology , cas9 , genetics , nanotechnology , gene , materials science
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom