The UCSC Genome Browser database: 2022 update
Author(s) -
Brian T. Lee,
Galt P Barber,
Anna BenetPagès,
Jonathan D. Casper,
Hiram Clawson,
Mark Diekhans,
Clay Fischer,
Jairo Navarro Gonzalez,
Angie S. Hinrichs,
Christopher M. Lee,
Pranav Muthuraman,
Luis R Nassar,
Beagan Nguy,
Tiana Pereira,
Gerardo Perez,
Brian J. Raney,
Kate R. Rosenbloom,
Daniel Schmelter,
Matthew L Speir,
Brittney Wick,
Ann S. Zweig,
David Haussler,
Robert M. Kuhn,
Maximilian Haeussler,
W. James Kent
Publication year - 2021
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkab959
Subject(s) - genome browser , decipher , genome , context (archaeology) , biology , software , usability , visualization , genomics , world wide web , computational biology , computer science , genetics , gene , data mining , human–computer interaction , paleontology , programming language
The UCSC Genome Browser, https://genome.ucsc.edu, is a graphical viewer for exploring genome annotations. The website provides integrated tools for visualizing, comparing, analyzing, and sharing both publicly available and user-generated genomic datasets. Data highlights this year include a collection of easily accessible public hub assemblies on new organisms, now featuring BLAT alignment and PCR capabilities, and new and updated clinical tracks (gnomAD, DECIPHER, CADD, REVEL). We introduced a new Track Sets feature and enhanced variant displays to aid in the interpretation of clinical data. We also added a tool to rapidly place new SARS-CoV-2 genomes in a global phylogenetic tree enabling researchers to view the context of emerging mutations in our SARS-CoV-2 Genome Browser. Other new software focuses on usability features, including more informative mouseover displays and new fonts.
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