SPICA: Swiss portal for immune cell analysis
Author(s) -
Massimo Andreatta,
Fabrice P.A. David,
Christian Iseli,
Nicolas Guex,
Santiago J. Carmona
Publication year - 2021
Publication title -
nucleic acids research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/gkab1055
Subject(s) - spica , context (archaeology) , biology , immune system , cell , cell type , computational biology , transcriptome , immunology , genetics , gene expression , physics , gene , paleontology , optics
Single-cell transcriptomics allows the study of immune cell heterogeneity at an unprecedented level of resolution. The Swiss portal for immune cell analysis (SPICA) is a web resource dedicated to the exploration and analysis of single-cell RNA-seq data of immune cells. In contrast to other single-cell databases, SPICA hosts curated, cell type-specific reference atlases that describe immune cell states at high resolution, and published single-cell datasets analysed in the context of these atlases. Additionally, users can privately analyse their own data in the context of existing atlases and contribute to the SPICA database. SPICA is available at https://spica.unil.ch.
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