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Codon catalog usage is a genome strategy modulated for gene expressivity
Author(s) -
Richard Grantham,
Christian Gautier,
Manolo Gouy,
Monique Jacobzone,
Raphaël Mercier
Publication year - 1981
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/9.1.213-b
Subject(s) - biology , gene , codon usage bias , genome , genetics , translation (biology) , nucleic acid , computational biology , start codon , stop codon , sequence (biology) , messenger rna
The nucleic acid sequence bank now contains 161 mRNAs, 43 new genes are added. One sequence, that of B. mori fibroin, is dropped due to uncertainty on the starting point for translation. Frequencies of all codons are given for each gene added and for each genome type in the total bank. A new series of correspondence analyses on codon use is presented, substantiating the genome hypothesis. Internal regulation of mRNA expression by different third base choices between quartet and duet codons is proposed for bacterial genes.

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