The release of high mobility group protein H6 and protamine gene sequences upon selective DNase I degradation of trout testis chromatin | Zendy

Beatriz Levy-Wilson | Zendy; LeRoy Kuehl | Zendy; Helen Dixon | Zendy

Open Access

The release of high mobility group protein H6 and protamine gene sequences upon selective DNase I degradation of trout testis chromatin

Author(s) -

Beatriz Levy-Wilson,

LeRoy Kuehl,

Helen Dixon

Publication year - 1980

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/8.13.2859

Subject(s) - biology , chromatin , protamine , dna , deoxyribonuclease i , trout , gene , high mobility group , microbiology and biotechnology , biochemistry , genetics , fish <actinopterygii> , base sequence , fishery , heparin

Limited digestion of trout testis nuclei with DNase I selectively degrades the protamine genes. Concomitant with the degradation of transcribed DNA sequences a series of chromosomal proteins are released; among these, the major species corresponds to the high mobility group protein H6. The amounts of H6 released from chromatin by limited DNase I action and that in the residual nuclear pellet have been determined. A very high proportion of H6 is associated with DNase I sensitive chromatin regions.

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