Open AccessGenes for ϒ-globin in human adult erythroid DNA
Author(s) -
Ga Mitchell,
R. Williamson
Publication year - 1977
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/4.10.3557
Subject(s) - biology , globin , gene , dna , genetics , microbiology and biotechnology
Purified gamma-globin specific complementary DNA has been used to demonstrate the presence of the gene for gamma-globin in DNA from human adult red blood cells. This finding sheds doubt on any theory involving looping-out excision of genes to explain the switch over from synthesis of gamma-globin to beta-globin at birth.
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