The Ensembl genome database project
Author(s) -
Tim Hubbard,
Darren Barker,
Ewan Birney,
Graham Cameron,
Y. Chen,
Louise Clark,
Tony Cox,
James Cuff,
V. Curwen,
Thomas A. Down,
Richard Durbin,
Eduardo Eyras,
James Gilbert,
M. Hammond,
Łukasz Huminiecki,
A. Kasprzyk,
Heikki Lehväslaiho,
Philip Lijnzaad,
Craig Melsopp,
Emmanuel Mongin,
Roger Pettett,
Matthew Pocock,
Simon Potter,
Alistair G. Rust,
E Schmidt,
Stephen M. J. Searle,
Guy Slater,
James Smith,
W. Spooner,
Arne Stabenau,
Jim Stalker,
Elia Stupka,
A. Ureta-Vidal,
Imre Västrik,
M. Clamp
Publication year - 2002
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/30.1.38
Subject(s) - ensembl , genome , genome project , annotation , biology , human genome , visualization , computational biology , software , genomics , world wide web , database , computer science , bioinformatics , genetics , gene , data mining , programming language
The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organise biology around the sequences of large genomes. It is a comprehensive source of stable automatic annotation of the human genome sequence, with confirmed gene predictions that have been integrated with external data sources, and is available as either an interactive web site or as flat files. It is also an open source software engineering project to develop a portable system able to handle very large genomes and associated requirements from sequence analysis to data storage and visualisation. The Ensembl site is one of the leading sources of human genome sequence annotation and provided much of the analysis for publication by the international human genome project of the draft genome. The Ensembl system is being installed around the world in both companies and academic sites on machines ranging from supercomputers to laptops.
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