Open AccessBiosynthesis of the modified nucleoside Q in transfer RNA
Author(s) -
Yoshiyuki Kuchino,
Hiroshi Kasai,
Kenichi Nihei,
Susumu Nishimura
Publication year - 1976
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/3.2.393
Subject(s) - biology , biosynthesis , nucleoside , transfer rna , guanine , biochemistry , nitrogen atom , stereochemistry , rna , gene , nucleotide , ring (chemistry) , chemistry , organic chemistry
During biosynthesis of the modified nucleoside Q, 7-(4,5-DIHYDROXYL-1-1-CYCLOPENTEN-3-YL-AMINOMETHYL)-7-DEAZAGUANOSINE, IN TRNA, the carbon atom at position 8 in precursor molecule guanine was expelled together with the nitrogen atom N-7 in a fashion similar to that in the biosynthesis of the nucleoside antibiotic toyocamycin.
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