Chromatin structure: a property of the higher structure of chromatin and the time course of its formation during chromatin replication | Zendy

L.A. Burgoyne | Zendy; Jennifer Mobbs | Zendy; A.J. Marshall | Zendy

Open Access

Chromatin structure: a property of the higher structure of chromatin and the time course of its formation during chromatin replication

Author(s) -

L.A. Burgoyne,

Jennifer Mobbs,

A.J. Marshall

Publication year - 1976

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/3.12.3293

Subject(s) - chromatin , biology , dna , microbiology and biotechnology , scaffold/matrix attachment region , dna replication , cell nucleus , genetics , chromatin remodeling , nucleus

The action of a number of enzymes and metals on one nuclear preparation were interpreted in terms of the existence of a fragile but highly DNAase-I resistant feature of chromatin superstructure. The generation of this DNAase-I resistance feature of chromatin was then followed during normal DNA synthesis in the regenerating rat liver by following the disappearance of a transitory DNAase-I susceptible state. This transitory, DNAase-I susceptible state appears to be extremely similar to the post-synthetic, DNAase-I susceptible state that has been described in He La32.

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