GeneSplicer: a new computational method for splice site prediction | Zendy

Mihaela Pertea | Zendy

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GeneSplicer: a new computational method for splice site prediction

Author(s) -

Mihaela Pertea

Publication year - 2001

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/29.5.1185

Subject(s) - splice , biology , computational biology , arabidopsis thaliana , dna , arabidopsis , genomic dna , genetics , rna splicing , computational model , gene , computer science , artificial intelligence , rna , mutant

GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

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