The TRANSFAC system on gene expression regulation | Zendy

Edgar Wingender | Zendy

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The TRANSFAC system on gene expression regulation

Author(s) -

Edgar Wingender

Publication year - 2001

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/29.1.281

Subject(s) - biology , transcription factor , gene , genetics , regulation of gene expression , gene expression , transcription (linguistics) , gene regulatory network , cis regulatory module , microbiology and biotechnology , promoter , computational biology , linguistics , philosophy

The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules. These modules give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction (TRANSPATH) and gene expression sources (CYTOMER). Altogether, these distinct database modules constitute the TRANSFAC system. They are accompanied by a number of program routines for identifying potential transcription factor binding sites or for localizing individual components in the regulatory network of a cell.

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