SURVEY AND SUMMARY A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter | Zendy

LEANDRO AUGUSTO GRANDIN PEREIRA | Zendy

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SURVEY AND SUMMARY A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter

Author(s) -

LEANDRO AUGUSTO GRANDIN PEREIRA

Publication year - 2000

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/28.3.663

Subject(s) - biology , long terminal repeat , hiv long terminal repeat , genetics , computational biology , human immunodeficiency virus (hiv) , transcription (linguistics) , transcription factor , dna , dna binding protein , virology , genome , gene , linguistics , philosophy

The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) represents a model promoter system and the identification and characterisation of cellular proteins that interact with this region has provided a basic understanding about both general eukaryotic and HIV-1 proviral transcriptional regulation. To date a large number of sequence-specific DNA-protein interactions have been described for the HIV-1 LTR. The aim of this report is to provide a comprehensive, updated listing of these HIV-1 LTR interactions. It is intended as a reference point to facilitate on-going studies characterising the identity of cellular proteins interacting with the HIV-1 LTR and the functional role(s) of specific regions of the LTR for HIV-1 replication.

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