z-logo
open-access-imgOpen Access
Mitochondrial RNAs of myxomycetes terminate with non-encoded 3' poly(U) tails
Author(s) -
Tamara L. Horton
Publication year - 2000
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/28.23.4750
Subject(s) - physarum polycephalum , biology , cytochrome c oxidase , protein subunit , physarum , messenger rna , microbiology and biotechnology , rna , oxidase test , gene , mitochondrion , biochemistry , enzyme
We examined the 3' ends of edited RNAs from the myxomycetes Stemonitis flavogenita and Physarum polycephalum using a modified anchor PCR approach. Surprisingly, we found that poly(A) tails are missing from the cytochrome c oxidase subunit 1 mRNA (coI) from both species and the cytochrome c oxidase subunit 3 mRNA (cox3) from P. polycephalum. Instead, non-encoded poly(U) tails of varying length were discovered at the 3' ends of these transcripts. These are the first described examples of 3' poly(U) tails on mature mRNAs in any system.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom