Increased coverage of protein families with the Blocks Database servers | Zendy

Jorja G. Henikoff | Zendy

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Increased coverage of protein families with the Blocks Database servers

Author(s) -

Jorja G. Henikoff

Publication year - 2000

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/28.1.228

Subject(s) - protein data bank (rcsb pdb) , biology , block (permutation group theory) , server , database , protein data bank , protein family , computational biology , bioinformatics , computer science , genetics , protein structure , world wide web , gene , combinatorics , biochemistry , mathematics

The Blocks Database WWW (http://blocks.fhcrc.org ) and Email (blocks@blocks.fhcrc.org ) servers provide tools to search DNA and protein queries against the Blocks+ Database of multiple alignments, which represent conserved protein regions. Blocks+ nearly doubles the number of protein families included in the database by adding families from the Pfam-A, ProDom and Domo databases to those from PROSITE and PRINTS. Other new features include improved Block Searcher statistics, searching with NCBI's IMPALA program and 3D display of blocks on PDB structures.

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