RegulonDB: a database on transcriptional regulation in Escherichia coli
Author(s) -
Alejandro Huerta
Publication year - 1998
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/26.1.55
Subject(s) - biology , operon , escherichia coli , transcription (linguistics) , transcriptional regulation , gene , genetics , promoter , escherichia coli proteins , regulation of gene expression , chromosome , computational biology , transcription factor , gene expression , linguistics , philosophy
RegulonDB is a DataBase that integrates biological knowledge of the mechanisms that regulate the transcription initiation in Escherichia coli , as well as knowledge on the organization of the genes and regulatory signals into operons in the chromosome. The operon is the basic structure used in RegulonDB to describe the elements and properties of transcriptional regulation. The current version contains information around some 500 regulation mechanisms, essentially for sigma 70 promoters.
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