aCHEdb: the database system for ESTHER, the alpha/beta fold family of proteins and the Cholinesterase gene server | Zendy

Xavier Cousin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

aCHEdb: the database system for ESTHER, the alpha/beta fold family of proteins and the Cholinesterase gene server

Author(s) -

Xavier Cousin

Publication year - 1998

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/26.1.226

Subject(s) - biology , hydrolase , enzyme , database , gene , beta (programming language) , alpha (finance) , biochemistry , genetics , microbiology and biotechnology , programming language , medicine , construct validity , nursing , computer science , patient satisfaction

Acetylcholinesterase belongs to a family of proteins, the alpha/beta hydrolase fold family, whose constituents evolutionarily diverged from a common ancestor and share a similar structure of a central beta sheet surrounded by alpha helices. These proteins fulfil a wide range of physiological functions (hydrolases, adhesion molecules, hormone precursors) [Krejci,E., Duval,N., Chatonnet,A., Vincens,P. and Massoulié,J. (1991) Proc. Natl. Acad. Sci. USA , 88, 6647-6651]. ESTHER (for esterases, alpha/beta hydrolase enzymes and relatives) is a database aimed at collecting in one information system, sequence data together with biological annotations and experimental biochemical results related to the structure-function analysis of the enzymes of the family. The major upgrade of the database comes from the use of a new database management system: aCHEdb which uses the ACeDB program designed by Richard Durbin and Jean Thierry-Mieg. It can be found at http://www.ensam.inra.fr/cholinesterase

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research