DIR: a novel DNA rearrangement associated with inverted repeats | Zendy

David J. Pinder | Zendy

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DIR: a novel DNA rearrangement associated with inverted repeats

Author(s) -

David J. Pinder

Publication year - 1997

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/25.3.523

Subject(s) - biology , inverted repeat , palindrome , gene duplication , direct repeat , gene rearrangement , genetics , sequence (biology) , dna , dna replication , base sequence , gene , genome

A novel DNA rearrangement has been characterised that is both a direct and inverted repeat. This rearrangement involves the 2-fold duplication of a plasmid sequence adjacent to the site of insertion of a long palindrome. The sequence of this rearrangement suggests that it has arisen by strand slippage from the leading to the lagging strand of the replication fork as a consequence of the presence of the long palindrome.

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