Recent enhancements to the Blocks Database servers | Zendy

Jorja G. Henikoff | Zendy; Shmuel Pietrokovski | Zendy; Steven Henikoff | Zendy

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Recent enhancements to the Blocks Database servers

Author(s) -

Jorja G. Henikoff,

Shmuel Pietrokovski,

Steven Henikoff

Publication year - 1997

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/25.1.222

Subject(s) - server , block (permutation group theory) , biology , database , web server , sequence database , tree (set theory) , protein family , sequence (biology) , computer science , world wide web , the internet , combinatorics , genetics , mathematics , gene

The Blocks Database contains multiple alignments of conserved regions in protein families which can be searched by e-mail (blocks@blocks.fhcrc.org) and World Wide Web (http://blocks.fhcrc.org/ ) servers to classify protein and nucleotide sequences. Recent enhancements to the servers include: (i) improved calculation of position-specific scoring matrices from blocks; (ii) availability of the Prints protein fingerprint database for searching in Blocks format; (iii) a representative sequence biased towards the Blocks of a protein family; (iv) a tree constructed from the Blocks of a protein family; (v) links to related World Wide Web pages for a family; and (vi) the new Local Alignment of Multiple Alignments (LAMA) method to search a block against a database of blocks.

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