MITOMAP: a human mitochondrial genome database | Zendy

Andreas M. Kogelnik | Zendy; Marie T. Lott | Zendy; Michael D. Brown | Zendy; Shamkant B. Navathe | Zendy; Douglas C. Wallace | Zendy

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MITOMAP: a human mitochondrial genome database

Author(s) -

Andreas M. Kogelnik,

Marie T. Lott,

Michael D. Brown,

Shamkant B. Navathe,

Douglas C. Wallace

Publication year - 1996

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/24.1.177

Subject(s) - biology , mitochondrial dna , genome , human genome , human mitochondrial genetics , genetics , gene , reference genome , computational biology

We have developed a comprehensive database (MITOMAP) for the human mitochondrial DNA (mtDNA), the first component of the human genome to be completely sequenced [Anderson et al. (1981) Nature 290, 457-465]. MITOMAP uses the mtDNA sequence as the unifying element for bringing together information on mitochondrial genome structure and function, pathogenic mutations and their clinical characteristics, population associated variation, and gene- gene interactions. As increasingly larger regions of the human genome are sequenced and characterized, the need for integrating such information will grow. Consequently, MITOMAP not only provides a valuable reference for the mitochondrial biologist, it may also provide a model for the development of information storage and retrieval systems for other components of the human genome.

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