Functional selection for the centromere DNA from yeast chromosome VIII | Zendy

Ursula Fleig | Zendy; J. Beinhauer | Zendy; Johannes H. Hegemann | Zendy

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Functional selection for the centromere DNA from yeast chromosome VIII

Author(s) -

Ursula Fleig,

J. Beinhauer,

Johannes H. Hegemann

Publication year - 1995

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/23.6.922

Subject(s) - centromere , biology , genetics , chromosome , human artificial chromosome , yeast , repeated sequence , yeast artificial chromosome , budding yeast , eukaryotic chromosome fine structure , saccharomyces cerevisiae , gene , genome , gene mapping

Centromeres are essential components of eucaryotic chromosomes. In budding yeast, up to now, 15 of the 16 centromere DNAs have been isolated. Here we report the functional isolation and characterization of CEN8, the last of the yeast centromeres missing. The centromere consensus sequence for the 16 chromosomes in this organism is presented.

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