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A possible role of the 5terminal sequence of 16S ribosomal RNA In the recognltton of Initiation sequences for protein synthesis
Author(s) -
P.H. van Knlppenberg
Publication year - 1975
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/2.1.79
Subject(s) - biology , rna , ribosome , shine dalgarno sequence , genetics , ribosomal rna , start codon , 5.8s ribosomal rna , base pair , ribosomal protein , non coding rna , microbiology and biotechnology , messenger rna , gene
Extensive complementarity is found between the 5' end of 16S ribosomal RNA and protein synthesis initiation sites of bacteriophage RNA. Hybrids can be constructed from base sequences of 16S-RNA and two initiation regions on phage RNA. A model is proposed for the involvement of 16S-RNA in the unfolding of hairpin loops containing the initiation codon AUG.

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