A possible role of the 5′terminal sequence of 16S ribosomal RNA In the recognltton of Initiation sequences for protein synthesis
Author(s) -
P.H. van Knlppenberg
Publication year - 1975
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/2.1.79
Subject(s) - biology , rna , ribosome , shine dalgarno sequence , genetics , ribosomal rna , start codon , 5.8s ribosomal rna , base pair , ribosomal protein , non coding rna , microbiology and biotechnology , messenger rna , gene
Extensive complementarity is found between the 5' end of 16S ribosomal RNA and protein synthesis initiation sites of bacteriophage RNA. Hybrids can be constructed from base sequences of 16S-RNA and two initiation regions on phage RNA. A model is proposed for the involvement of 16S-RNA in the unfolding of hairpin loops containing the initiation codon AUG.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom