The sequence of cDNA of bovine coronavirus 32K nonstructural gene | Zendy

Grahma J. Cox | Zendy; Michael D. Parker | Zendy; Lorne A. Babiuk | Zendy

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The sequence of cDNA of bovine coronavirus 32K nonstructural gene

Author(s) -

Grahma J. Cox,

Michael D. Parker,

Lorne A. Babiuk

Publication year - 1989

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/17.14.5847

Subject(s) - biology , complementary dna , gene , sequence (biology) , genetics , virology , nucleic acid sequence , coronavirus , sequence analysis , sequence alignment , peptide sequence , computational biology , covid-19 , medicine , disease , pathology , infectious disease (medical specialty)

In addition to the four structural proteins of bovine coronavirus a minimum of four virus-encoded nonstructural proteins are found in infected cell3. The nucleotide sequence of the NS 32 is presented. The gene is situated immediately upstream from the E3 gene and terminates within the NS32-E3 conserved intergenic region'. An ORF extends from nucleotides 15 to 845 and the computer generated translational product of 32K is in agreement with our observations (unpublished) and reports for other coronaviruses'. In addition to the conserved intergenic region (single underline) this gene shares homology (65% at the nt level, 45% at the aa level) with the ORF-1 in mRNA2 of MHVA59.

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