Conserved features of coordinately regulatedE.colipromoters | Zendy

Andrew Travers | Zendy

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Conserved features of coordinately regulatedE.colipromoters

Author(s) -

Andrew Travers

Publication year - 1984

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/12.6.2605

Subject(s) - biology , promoter , conserved sequence , genetics , gene , transfer rna , nucleic acid sequence , consensus sequence , rna polymerase , peptide sequence , microbiology and biotechnology , escherichia coli , rna , gene expression

E. coli promoters which are coordinately regulated in response to amino acid limitation contain conserved nucleotide sequences immediately 3' to -10 region. These sequences contain predominantly either GC or AT residues depending on whether the response is respectively negative or positive. Certain classes of promoters also contain conserved sequences upstream of the primary promoter. In tRNA genes these sequences could act as a secondary polymerase binding site.

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