Homology between theKpnI primate andBamHI (M1F-1) rodent families of long interspersed repeated sequences
Author(s) -
Maxine Singer,
Ronald E. Thayer,
Giovanna Grimaldi,
Michael I. Lennan,
Thomas G. Fanning
Publication year - 1983
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/11.16.5739
Subject(s) - biology , homology (biology) , genetics , repeated sequence , rodent , primate , evolutionary biology , dna , genome , gene , ecology , neuroscience
The KpnI and BamH1 (or M1F-1) families are the predominant sets of long interspersed repeated DNA sequences (LINEs) in primates and rodents, respectively. Recently, the sequences of several cloned subsegments from each family were determined in different laboratories. These sequences have now been compared and found to be homologous over at least 1400 bp. The data suggest that the two LINE families had a common progenitor and have been conserved in similar abundance although in divergent forms in the two mammalian orders.
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