Transcription of the ‘non-transcribed’ spacer ofDrosophila melanogasterrDNA | Zendy

J. Ross Miller | Zendy; David C. Hayward | Zendy; David M. Glover | Zendy

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Transcription of the ‘non-transcribed’ spacer ofDrosophila melanogasterrDNA

Author(s) -

J. Ross Miller,

David C. Hayward,

David M. Glover

Publication year - 1983

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/11.1.11

Subject(s) - biology , drosophila melanogaster , nucleotide , transcription (linguistics) , internal transcribed spacer , melanogaster , genetics , spacer dna , homologous chromosome , ribosomal rna , rna , microbiology and biotechnology , gene , linguistics , philosophy

We have detected a set of transcripts in Drosophila melanogaster cells which are homologous to repeating elements within the 'non-transcribed' spacer region of rDNA. The RNA molecules range from 240 to 1680 nucleotides, differing in length by an integral value of 240 nucleotides. We have sequenced several AluI fragments which characterise the main 240 nucleotide repeating element. We find that each of these fragments contain a segment of approximately 50 nucleotides, which is homologous to the transcription initiation site for pre-rRNA.

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