The nucleotide sequence ofaroG, the gene for 3-deoxy-D-arabinobeptulosonate-7-phosphate synthetase (phe) inEscherichia coliK12 | Zendy

W.David Davies | Zendy; Barrie E. Davidson | Zendy

Open Access

The nucleotide sequence ofaroG, the gene for 3-deoxy-D-arabinobeptulosonate-7-phosphate synthetase (phe) inEscherichia coliK12

Author(s) -

W.David Davies,

Barrie E. Davidson

Publication year - 1982

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/10.13.4045

Subject(s) - biology , nucleic acid sequence , gene , biochemistry , escherichia coli , peptide sequence , nucleotide , structural gene , amino acid , microbiology and biotechnology , genetics

We have determined the nucleotide sequence of aroG, the gene coding for 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase(phe), one of three isoenzymes that catalyse the first step of the biosynthesis of aromatic amino acids and vitamins in Escherichia coli K12. The DNA sequence agrees with previously published data on the N-terminal sequence, amino acid composition, and subunit molecular weight of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase(pne). There is significant identity in the nucleotide sequences of aroG and aroH (the gene for 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase (trp), indicating that these two genes have evolved from a common ancestral gene. There is no attenuator structure in the leader region of aroG.

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