Codon preference and its use in identifying protein coding regions in long DNA sequences
Author(s) -
Rodger Staden,
A.D. McLachian
Publication year - 1982
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/10.1.141
Subject(s) - biology , codon usage bias , genetics , exon , computational biology , intron , dna sequencing , coding region , preference , dna , coding (social sciences) , gene , genome , statistics , mathematics
This paper describes a computer method that uses codon preference to help find protein coding regions in long DNA sequences. The method can distinguish between introns and exons and can help to detect sequencing errors.
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