NanoGenotoxicology: present and the future
Author(s) -
Shareen H. Doak,
Mária Dušinská
Publication year - 2016
Publication title -
mutagenesis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.723
H-Index - 91
eISSN - 1464-3804
pISSN - 0267-8357
DOI - 10.1093/mutage/gew066
Subject(s) - genotoxicity , risk analysis (engineering) , mutagenesis , computational biology , biochemical engineering , computer science , nanotechnology , biology , chemistry , engineering , business , genetics , mutation , toxicity , materials science , organic chemistry , gene
This Mutagenesis special issue is on the topic of nanogenotoxicology. It unites a collection of reports that provide insight into: (i) the properties of engineered nanomaterials (ENMs) that contribute to genotoxicity, (ii) the genotoxic mechanisms associated with DNA damage observed in both in vitro and in vivo tests and (iii) the future test systems that will provide more accurate prediction of ENM genotoxicity to support regulatory hazard assessment frameworks. The contributions within therefore provide collective oversight of our current understanding, coupled to future perspectives aimed at overcoming technical hurdles and describing novel analytical methods to further advance the field.
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