Induction of micronuclei in mice exposed to static magnetic fields | Zendy

Yuji Suzuki | Zendy

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Induction of micronuclei in mice exposed to static magnetic fields

Author(s) -

Yuji Suzuki

Publication year - 2001

Publication title -

mutagenesis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.723

H-Index - 91

eISSN - 1464-3804

pISSN - 0267-8357

DOI - 10.1093/mutage/16.6.499

Subject(s) - micronucleus test , micronucleus , clastogen , bone marrow , biology , chemistry , microbiology and biotechnology , immunology , toxicity , organic chemistry

The aim of this experiment was to investigate whether static magnetic fields (SMFs) have cytogenetic effects in mouse bone marrow cells. The frequency of micronuclei was significantly increased by exposure of mice to 3.0 T for 48 and 72 h and 4.7 T for 24, 48 and 72 h. The increase in micronucleus frequency was dose dependent at all times. Micronucleus frequency at 4.7 T was higher than at 3.0 T. We consider that the increased numbers of micronuclei may be attributable to a stress reaction caused by SMFs or a direct clastogenic/spindle disturbance effect of SMFs.

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