In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome
Author(s) -
Mariana Di Pietro,
Natalia Pascuali,
Leopoldina Scotti,
Griselda Irusta,
Diana Bas,
María May,
Marta Tesone,
Dalhia Abramovich,
Fernanda Parborell
Publication year - 2017
Publication title -
molecular human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.143
H-Index - 122
eISSN - 1460-2407
pISSN - 1360-9947
DOI - 10.1093/molehr/gax021
Subject(s) - ovarian hyperstimulation syndrome , ovary , endocrinology , medicine , biology , sphingosine 1 phosphate , sphingosine , in vivo , andrology , in vitro fertilisation , pregnancy , receptor , genetics , microbiology and biotechnology
Can the bioactive lipid sphingosine-1 phosphate (S1P) act as an endothelial barrier-enhancing molecule and, in turn, restore the vascular integrity and homoeostasis in a rat model of ovarian hyperstimulation syndrome (OHSS).
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