Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes | Zendy

Eryn Dutta | Zendy; Faranak Behnia | Zendy; István Boldogh | Zendy; George R. Saade | Zendy; Brandie D. Taylor | Zendy; Marian Kacerovský | Zendy; Ramkumar Me | Zendy

Open Access

Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes

Author(s) -

Eryn Dutta,

Faranak Behnia,

István Boldogh,

George R. Saade,

Brandie D. Taylor,

Marian Kacerovský,

Ramkumar Me

Publication year - 2015

Publication title -

molecular human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.143

H-Index - 122

eISSN - 1460-2407

pISSN - 1360-9947

DOI - 10.1093/molehr/gav074

Subject(s) - oxidative stress , senescence , dna damage , biology , signal transduction , reactive oxygen species , microbiology and biotechnology , endocrinology , biochemistry , dna

In women with preterm premature rupture of the membranes (PPROM), increased oxidative stress may accelerate premature cellular senescence, senescence-associated inflammation and proteolysis, which may predispose them to rupture.

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