Embryo-uterine cross-talk during implantation: the role of Wnt signaling | Zendy

Qi Chen | Zendy; Ying Zhang | Zendy; JinJian Lu | Zendy; Qiang Wang | Zendy; Sheng Wang | Zendy; Yu Cao | Zendy; Haoyu Wang | Zendy; Enkui Duan | Zendy

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Embryo-uterine cross-talk during implantation: the role of Wnt signaling

Author(s) -

Qi Chen,

Ying Zhang,

JinJian Lu,

Qiang Wang,

Sheng Wang,

Yu Cao,

Haoyu Wang,

Enkui Duan

Publication year - 2009

Publication title -

molecular human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.143

H-Index - 122

eISSN - 1460-2407

pISSN - 1360-9947

DOI - 10.1093/molehr/gap009

Subject(s) - wnt signaling pathway , decidualization , biology , blastocyst , embryo , pregnancy , microbiology and biotechnology , signal transduction , andrology , embryogenesis , genetics , medicine

During mammalian pregnancy, it has been demonstrated that the quality of embryo implantation determines the quality of ongoing pregnancy and fetal development. Recent studies have provided increasing evidence that differential Wnt signaling plays diverse roles in multiple peri-implantation events. This review focuses on recent progress on various aspects of Wnt signaling in preimplantation embryo development, blastocyst activation for implantation and uterine decidualization. Future studies with conditional deletion of Wnt family members are hoped to provide deeper insight on the pathophysiological significance of Wnt proteins on early pregnancy events.

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