Open AccessDnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets
Author(s) -
Julio Rozas,
Albert Ferrer-Mata,
Juan Carlos Sánchez-DelBarrio,
Sara GuiraoRico,
Pablo Librado,
Sebastián E. RamosOnsins,
Alejandro SánchezGracia
Publication year - 2017
Publication title -
molecular biology and evolution
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.637
H-Index - 218
eISSN - 1537-1719
pISSN - 0737-4038
DOI - 10.1093/molbev/msx248
Subject(s) - biology , coalescent theory , computational biology , dna sequencing , scalability , locus (genetics) , software , population , genetics , computer science , dna , database , gene , programming language , phylogenetics , demography , sociology
We present version 6 of the DNA Sequence Polymorphism (DnaSP) software, a new version of the popular tool for performing exhaustive population genetic analyses on multiple sequence alignments. This major upgrade incorporates novel functionalities to analyze large data sets, such as those generated by high-throughput sequencing technologies. Among other features, DnaSP 6 implements: 1) modules for reading and analyzing data from genomic partitioning methods, such as RADseq or hybrid enrichment approaches, 2) faster methods scalable for high-throughput sequencing data, and 3) summary statistics for the analysis of multi-locus population genetics data. Furthermore, DnaSP 6 includes novel modules to perform single- and multi-locus coalescent simulations under a wide range of demographic scenarios. The DnaSP 6 program, with extensive documentation, is freely available at http://www.ub.edu/dnasp.
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