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ExaBayes: Massively Parallel Bayesian Tree Inference for the Whole-Genome Era
Author(s) -
Andre J. Aberer,
Kassian Kobert,
Alexandros Stamatakis
Publication year - 2014
Publication title -
molecular biology and evolution
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.637
H-Index - 218
eISSN - 1537-1719
pISSN - 0737-4038
DOI - 10.1093/molbev/msu236
Subject(s) - massively parallel , supercomputer , inference , bayesian probability , computer science , tree (set theory) , software , biology , bayesian inference , parallel computing , theoretical computer science , computational biology , artificial intelligence , programming language , mathematics , mathematical analysis
Modern sequencing technology now allows biologists to collect the entirety of molecular evidence for reconstructing evolutionary trees. We introduce a novel, user-friendly software package engineered for conducting state-of-the-art Bayesian tree inferences on data sets of arbitrary size. Our software introduces a nonblocking parallelization of Metropolis-coupled chains, modifications for efficient analyses of data sets comprising thousands of partitions and memory saving techniques. We report on first experiences with Bayesian inferences at the whole-genome level using the SuperMUC supercomputer and simulated data.

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