Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates | Zendy

Kurt L. Harris | Zendy; Raine E. S. Thomson | Zendy; Yosephine Gumulya | Zendy; Gabriel Foley | Zendy; Saskya E. Carrera-Pacheco | Zendy; Parnayan Syed | Zendy; Tomasz Janosik | Zendy; Ann-Sofie Sandinge | Zendy; Shalini Andersson | Zendy; Ulrik Jurva | Zendy; Mikael Bodén | Zendy; Elizabeth M. J. Gillam | Zendy

Open Access

Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates

Author(s) -

Kurt L. Harris,

Raine E. S. Thomson,

Yosephine Gumulya,

Gabriel Foley,

Saskya E. Carrera-Pacheco,

Parnayan Syed,

Tomasz Janosik,

Ann-Sofie Sandinge,

Shalini Andersson,

Ulrik Jurva,

Mikael Bodén,

Elizabeth M. J. Gillam

Publication year - 2022

Publication title -

molecular biology and evolution

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.637

H-Index - 218

eISSN - 1537-1719

pISSN - 0737-4038

DOI - 10.1093/molbev/msac116

Subject(s) - biology , xenobiotic , cytochrome p450 , evolutionary biology , lineage (genetic) , phylogenetics , molecular evolution , monooxygenase , extant taxon , aryl hydrocarbon receptor , vertebrate , genetics , enzyme , gene , biochemistry , transcription factor

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