Different risk factors for candidemia occur for Candida species belonging to the C. parapsilosis complex | Zendy

Caroline Collioni Constante | Zendy; A. Monteiro | Zendy; Sydney Hartz Alves | Zendy; Lí­lian Carla Carneiro | Zendy; Michel Mansur Machado | Zendy; Luiz Carlos Severo | Zendy; S. Park | Zendy; David S. Perlin | Zendy; Alessandro C. Pasqualotto | Zendy

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Different risk factors for candidemia occur for Candida species belonging to the C. parapsilosis complex

Author(s) -

Caroline Collioni Constante,

A. Monteiro,

Sydney Hartz Alves,

Lílian Carla Carneiro,

Michel Mansur Machado,

Luiz Carlos Severo,

S. Park,

David S. Perlin,

Alessandro C. Pasqualotto

Publication year - 2014

Publication title -

medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.004

H-Index - 86

eISSN - 1460-2709

pISSN - 1369-3786

DOI - 10.1093/mmy/myt034

Subject(s) - candida parapsilosis , sensu stricto , biology , microbiology and biotechnology , fluconazole , antifungal , medicine , zoology

Previous studies have demonstrated reduced virulence in the species that comprise the Candida parapsilosis complex. We investigated a cohort of 93 patients with candidemia caused by this complex. Most infections were caused by C. parapsilosis (80.6%), followed by C. orthopsilosis (18.3%) and C. metapsilosis (1.1%). Renal failure (P < 0.001) and chronic liver diseases (P = 0.019) were more frequently encountered with infections caused by the C. orthopsilosis group, suggesting an association with patients who had a greater state of immune suppression in comparison with infections caused by C. parapsilosis sensu stricto.

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