A Case of Hodgkin Lymphoma Mimicking Lymphomatoid Granulomatosis Diagnosed at Autopsy
Author(s) -
Sujal I. Shah,
Megan Smith,
Randall Butler
Publication year - 2017
Publication title -
laboratory medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.332
H-Index - 28
eISSN - 1943-7730
pISSN - 0007-5027
DOI - 10.1093/labmed/lmx065
Subject(s) - lymphomatoid granulomatosis , medicine , autopsy , pathology , lymphoma
Hodgkin lymphoma and lymphomatoid granulomatosis (LYG) are entities that contain a small number of large, variably Epstein-Barr virus (EBV)-positive neoplastic cells scattered within background non-neoplastic mixed inflammatory infiltrate. The 2 entities can typically be distinguished histologically by the angiocentric and angiodestructive pattern of lymphomatoid granulomatosis (LYG); also, they differ in overall prognosis. Herein, we report a case of Hodgkin lymphoma in a 64-year-old Caucasian woman, diagnosed at autopsy with unusual histologic features and aggressive clinical course that mimicked LYG.
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