Acute Myeloid Leukemia With a Rare t(7;14)(q21;q32) and Trisomy 4 With Poor Clinical Outcome: A Case Report | Zendy

Seema B. Jabbar | Zendy; Sara A. Monaghan | Zendy; Weina Chen | Zendy; Prasad Koduru | Zendy; K. Shiva Kumar | Zendy

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Acute Myeloid Leukemia With a Rare t(7;14)(q21;q32) and Trisomy 4 With Poor Clinical Outcome: A Case Report

Author(s) -

Seema B. Jabbar,

Sara A. Monaghan,

Weina Chen,

Prasad Koduru,

K. Shiva Kumar

Publication year - 2017

Publication title -

laboratory medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.332

H-Index - 28

eISSN - 1943-7730

pISSN - 0007-5027

DOI - 10.1093/labmed/lmx034

Subject(s) - myeloid leukemia , trisomy , bone marrow , trisomy 8 , cytogenetics , induction chemotherapy , myeloid , leukemia , medicine , aneuploidy , pathology , chemotherapy , oncology , cancer research , immunology , biology , chromosome , genetics , gene

Recurrent cytogenetic abnormalities and/or molecular aberrations play an important role in the diagnosis and prognostification of acute myeloid leukemia (AML). We describe a case of a 40 year old woman diagnosed with de novo AML with a novel t(7;14)(q21,q32) and trisomy 4 with poor clinical outcome. Methods: Morphologic, flow cytometry and cytogenetic results of the patient's peripheral blood and bone marrow samples were analyzed.

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